Yini i-Red Devil chemo?

I-chemotherapy (“chemo”) idlula “i-Red Devil” ngumuthi we-doxorubicin (Adriamycin). Le ndlula yezifo zasendle ngokugcwalisa, enobala obukhulu obumnyama, okuyindlela eyathola igama lakhe elithile.

Yini uhlobo lwesifo esetshenziselwa i-Red Devil?

Eminyakeni eminingi edlule, idlula yezifo i-doxorubicin ibe yingxenye yezindlela zokwelapha abantu abanokuthola izifo eziningi, kufaka phakathi isifo sezibele kanye neleukemia.

Yini okwenza i-Red Devil chemo emzimbeni wakho?

Lesi sithako siqashelwe igama elibi, i-red devil, esuselwe emibala yayo ebomvu (i-Kool-Aid red), izici zokugcina, kanye nendlela yokusebenza yayo, okuhlanganisa ukwehla komzimba, ukuncipha kwamandla, ukuguleka nokuphuka, imilenze emlonyeni, kanye nokugula okungaqondakali kodwa okubalulekile kwezinzwa.

Yiziphi izici ezide ze-Red Devil Chemo?

Izici ezide zangaphakathi ezivezwe ngokusebenzisa i-Adriamycin zihlanganisa: Amagciwane omhlane noma amagciwane esisu. Ukubonakala kwesilwane noma umlomo we-oral mucosa (okungaqondakali). Ukugula nokufa kwenhliziyo, ikakhulukazi i-cecum (okungaqondakali).

Ingabe i-doxorubicin yindlela ephezulu kakhulu ye-chemo?

I-Doxorubicin ibhekwa njengendlela ephezulu kakhulu yokwelapha isifo sezibele kusukela kudalelwe. Ingakubulala izinkalankala zesifo ngamunye emoyeni wazo, futhi isetshenziswa ukwelapha izifo eziningi, hhayi nje isifo sezibele nje.

UBUDE BENDLELA: UKULWA NE-RED DEVIL

Ubani ozothola ukwelashwa ngokweqile?

I-Doxorubicin, eklasini yamadwala abizwa ngokuthi anthracyclines, isetshenziswe iminyaka eminingi ekwelapheni izifo ezahlukahlukene ezifana nokhansela kwamabele noma okhansela kwamagugu, noma izifo zegazi njenge-leukemia noma i-lymphoma.

Yini inqubomgomo yokuphila kwedoxorubicin?

Ekulandeleni okwama-56, inqubomgomo yokuphila, iphuzu lokugcina, ngenyanga eyodwa kwakukhona ukuphakama okuncane, kodwa akukho okuqinile, ngokuhlanganiswa; inqubomgomo yokuphila kwakungu-60% nge-ifosfamide/doxorubicin ngokulinganiswa ne-51% nge-doxorubicin kuphela, isilinganiselo se-HR 0.82; p = 0.061.

Ukwelashwa ngokweqile kuchitha isikhathi sokuphila ngosuku?

Phakathi kweminyaka engu-3, ingxenye yabaphilayo abelashwe ngokweqile kuphela yanda kusuka ku-18% ngo-1970-1979 kuya ku-54% ngo-1990-1999, futhi umehluko wokuphila kwesikhathi eside kuleli qembu elilashwe ngokweqile kuphela yehla kusuka konyaka we-11.0 (95% UI, 9.0-13.1 years) kuya konyaka we-6.0 (95% UI, 4.5-7.6 years).

Yini igama leqiniso lokwelashwa ngokweqile?

I-Doxorubicin (Adriamycin) yilona qedela elinamandla kakhulu kwamadwala weqiniso. Ungabulala izinkulungwane zokhansela ngamunye ngaphakathi kwemizamo yabo yempilo, futhi usebenziswa ekwelapheni izinhlobo eziningi zokhansela. Ngeke kwenzeke, amadwala angaphazamisi namacell weqiniso, ngakho umuntu engakwazi ukuyithatha ngaphakathi.

Iminyaka emingaki i-chemo ihlala emzimbeni wakho?

Ngokuvamile kuyadingeka ama-48 kuya ku-72 amahora ukuze umzimba wakho ubhucule noma ukhiphe imithi ye-chemo. Kodwa kubalulekile ukwazi ukuthi imithi ngayinye ye-chemo ivunyelwana noma iphuma emzimbeni ngendlela ehlukile.

Ukuthi i-2nd chemo ibi kuneqembu le-1?

Ungahleli ukuphendula kwakho ku-chemo kuze uqede ukungena kwakho kwokuqala. Izinga lokusebenza kwe-chemo liyazwakala. Ligcwele ngamunye umjikelezo.

Ingabe evikini leqembu le-1 ngemva kwe-chemo kungcono?

Abaningi abantu izinkinga zabo zazibi kakhulu emihlanu yokuqala ngemva kwesiko, bese ngokunciphisa bagcina bakhululeka kuze kube nesandla esilandelayo. Abanye bathi izinkinga zazibi kakhulu ngokulandelana kwemisebenzi. Izinkinga eziningi azigcini futhi ziyaphela ngemva kwezinsuku ezimbalwa ngemva kokugcina kwesiko.

Yikuphi okungukunqoba kakhulu kwezinkinga zika-doxorubicin?

Lesi sithako singenza ukuthi kudonswa izinhliziyo zezinhlamvu zezinhliziyo, okuzokwenza kube nokungasebenzi kahle kwenhliziyo. Lokhu kungenzeka kakhulu uma unezinkinga zezinhliziyo ezinye, unezibonelelo zokushaywa ngemithi kwezifuba zakho, noma unezibonelelo zokwelapha kwezifo.

Yiziphi izinhlobo ezintathu zezinkumba ezibulalayo kakhulu?

Yiziphi izinkumba ezibulalayo?

Ukulungiswa kwe-phaphu ne-bronchus kubangela ukufa okuningi kakhulu ngokuthi abantu abangu-130,180 balindele ukufa ngalesi sifo. Lokhu kuyisigamu esingu-3 kwezinye izigamu ezingama-52,580 ukufa ngenxa yesifo sokuqala esibulala kakhulu. Isifo sokuqala esibulala kakhulu kuyi-cancer yepankriyas, esibulala abantu abangu-49,830.

Yiziphi izinhlobo ezingu-7 eziphambili zezokwelapha?

Yiziphi izinkumba ezinakho ukwelaphwa nge-chemotherapy?

Izibonelo zezinkumba lapho izokwelapha zisebenza kahle kakhulu kukhona isifo sokugula kwamathende kanye ne-Hodgkin lymphoma. Ngamanye amacancers, izokwelapha azikwazi ukwelapha isifo sodwa. Kodwa kungasiza ngokuhlanganiswa nezinye izinhlobo zezokwelapha.

Kwenzakalani ngemva kokwelithathu lokwelashwa ngokuhlanza igazi?

Ungakwazi ukuzizwa ukunyanyalala (ukuzizwa sengathi uzoklulaza) nokululaza (ukululaza) ngemva kokugcina ukwelashwa ngokuhlanza igazi. Kufanele lihambe ngemuva kwemaviki angu-2 kuya ku-3. Ukuthanda ukudla kwakho kungase kugcinwe kuhlaselwe ngokushintsha kwendlebe yendlela oyithandayo ngenkathi yezokwelashwa kwakho.

Ungaphila impilo ejwayelekile ngemva kokwelashwa ngokuhlanza igazi?

Ukubuya emuva kwempilo ejwayelekile kuyinto evamile, kodwa kuthatha isikhathi – ngokuvamile izinyanga ezingu-6 noma ngaphezulu. “Bonke abaqede ukwelashwa ngokuhlanza igazi bayabuya emuva kwempilo ejwayelekile,” kusho uPatricia. “Ukwehluleka kwezinqubo zokwelashwa kwegazi lingathatha unyaka wonke, kodwa ngenyanga ezingu-6 ngemva kokuphela kwazo, impilo ibuya – izilonda zivala, izinwele zikhula, ukucabanga okungajwayelekile ngokuhlanza igazi kuyaphela.”